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Most experts are of the consensus that Peyronie's disease usually develops following a trauma or injury that causes bleeding inside the penis. However, while this trauma may explain acute cases of Peyronie's disease, it does not explain why most cases develop slowly and progressively (chronic cases), or what causes the disease after no apparent traumatic event or accident.
What happens in Peyronie's disease?
Peyronie's disease is characterized by a plaque, or hard lump, that forms on the erection tissue of the penis. Fortunately, this plaque is benign (or non-cancerous) and often begins as an inflammation that may develop into a fibrous tissue. In most of the cases, when the disease heals within a year or so, the plaque does not progress beyond an initial inflammatory phase. However, when the disease lasts for years, the plaque often becomes a tough, fibrous tissue, and calcium deposits may form.
